منابع مشابه
Cystatin C in macular and neuronal degenerations: Implications for mechanism(s) of age-related macular degeneration
Cystatin C is a strong inhibitor of cysteine proteinases expressed by diverse cells. Variant B cystatin C, which was associated with increased risk of developing age-related macular degeneration, differs from the wild type protein by a single amino acid (A25T) in the signal sequence responsible for its targeting to the secretory pathway. The same variant conveys susceptibility to Alzheimer dise...
متن کاملFixation in patients with juvenile macular disease.
PURPOSE The instability of fixation with central scotoma has been mainly studied in patients with age-related macular diseases (MDs). However, early macular lesions can lead to different characteristics of fixation. The aim of this work was to study fixation in patients with juvenile MD. METHODS Eye movements of 10 patients and 10 controls were monitored during fixation. Visual fields were as...
متن کاملAccommodation in humans with juvenile macular degeneration
Accommodation, or the change in refractive power of the eye to focus objects at different distances, is driven by many stimuli including defocus blur, the awareness of target distance or proximal cues, and through the vergence crosslink (convergence accommodation). The effectiveness of defocus blur as an accommodative stimulus is decreased in normally-sighted subjects as visual acuity is experi...
متن کاملMacular hole in juvenile X-linked retinoschisis.
An 18 year-old male with no antecedent of trauma, systemic syndrome or myopia was referred for surgical treatment of a full thickness macular hole in the left eye. A more careful inspection revealed discrete foveal cystic changes in the fellow eye and subtle peripheral depigmented retinal pigment epithelial changes in both eyes. A spectral-domain optical coherence tomography (SD-OCT) scan confi...
متن کاملA Case of Juvenile Disciform Macular Degeneration
The juvenile disciform macular degeneration is a non-inflammatory condition occurring in young people during the second and third decades tending to resolve in the course of a few months. de Schweinitz (1926), Junius (1930), and Davis and Sheppard (1935) have described cases ?f macular lesion similar to the senile disciform degeneration occurring in young subjects. The ophthalmoscopic examinati...
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ژورنال
عنوان ژورنال: Seminars in Pediatric Neurology
سال: 2017
ISSN: 1071-9091
DOI: 10.1016/j.spen.2017.05.005